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T-050

Supelco

Temazepam glucuronide lithium salt solution

100 μg/mL in methanol (as free carboxylate), ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Temazepam Glucuronide Solution

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About This Item

Fórmula empírica (notación de Hill):
C22H20ClLiN2O8
Peso molecular:
482.80
EC Number:
200-659-6
MDL number:
MFCD29918103
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland)

concentration

100 μg/mL in methanol (as free carboxylate)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

[Li+].CN1C(=O)C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C([O-])=O)N=C(c3ccccc3)c4cc(Cl)ccc14

InChI

1S/C22H21ClN2O8.Li/c1-25-13-8-7-11(23)9-12(13)14(10-5-3-2-4-6-10)24-19(20(25)29)33-22-17(28)15(26)16(27)18(32-22)21(30)31;/h2-9,15-19,22,26-28H,1H3,(H,30,31);/q;+1/p-1/t15-,16-,17+,18-,19?,22-;/m0./s1

InChI key

RQHXRNLYSZXQKI-NMJPLRNWSA-M

General description

The major urinary and blood metabolite of temazepam, an intermediate-acting 3-hydroxy benzodiazepine prescribed for the short-term treatment of sleeplessness in patients with difficulties remaining asleep. This new Certified Reference Standard is suitable for a variety of LCMS and GCMS applications, including forensic and forensic toxicology analysis, urine drug testing, and hydrolysis controls.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

G W Kunsman et al.
Journal of chromatography, 568(2), 427-436 (1991-08-23)
A rapid and sensitive method for extracting temazepam from human serum and urine is presented. Free temazepam is extracted from plasma and urine samples using n-butyl chloride with nitrazepam as the internal standard. Temazepam glucuronide is analyzed as free temazepam
Commentary on: Dou C, Bournique J, Zinda M, Gnezda M, Nally A, Salamone S. Comparison of rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E. coli beta-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer.
Carol L O'Neal et al.
Journal of forensic sciences, 47(2), 427-428 (2002-03-23)

Protocolos

UHPLC/MS for Drug Detection in Urine

Optimize β-glucuronidase hydrolysis for glucuronide metabolite analysis considering factors like time, temperature, pH, and enzyme concentration.

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