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Merck

850461C

Avanti

16:0-22:6 PC

Avanti Research - A Croda Brand

Sinónimos:

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine; PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

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About This Item

Fórmula empírica (notación de Hill):
C46H80NO8P
Número de CAS:
Peso molecular:
806.10
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850461C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (850461C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C46H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-24-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-19-17-15-13-11-9-7-2/h8,10,14,16,20-21,23-24,27,29,33,35,44H,6-7,9,11-13,15,17-19,22,25-26,28,30-32,34,36-43H2,1-5H3/b10-8-,16-14-,21-20-,24-23-,29-27-,35-33-/t44-/m1/s1

InChI key

IESVDEZGAHUQJU-ZLBXKVHBSA-N

Categorías relacionadas

General description

16:0-22:6 PC or 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine is a glycerophospholipid, with substitution of palmitic acid and docosahexaenic acid at sn-1 and sn-2 positions of the glycerol backbone, respectively.

Application

16:0-22:6 PC or 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine:
  • has been used in vesicle preparation
  • has been used in liposome extrusion and liposome flotation assay
  • might be used in large unilamellar vesicles (LUVs) to develop a scattering density profile (SDP) model for lipids with polyunsaturated fatty acid (PUFA)

Packaging

5 mL Clear Glass Sealed Ampule (850461C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


Certificados de análisis (COA)

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A universal method for planar lipid bilayer formation by freeze and thaw
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Soft Matter, 8(20), 5525-5531 (2012)
Drew Marquardt et al.
Chemistry and physics of lipids, 229, 104892-104892 (2020-02-18)
We present the detailed structural analysis of polyunsaturated fatty acid-containing phospholipids namely, 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine (PDPC) and 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine (SDPC). A newly developed molecular dynamics (MD) simulation parsing scheme for lipids containing fatty acids with multiple double bonds was implemented into the scattering
Anddre Osmar Valdivia et al.
ACS omega, 5(25), 15454-15467 (2020-07-09)
Multiple sclerosis has complex pathogenesis encompassing a variety of components (immunologic, genetic, and environmental). The autoimmunogenicity against the host's myelin basic protein is a major contributor. An increase in myelin basic protein deimination (a post-translational modification) and a change in

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