850350C

15:0 PC

1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, chloroform

• Sinónimos: PC(15:0/15:0)
• Fórmula empírica (notación de Hill): C₃₈H₇₆NO₈P
• Número de CAS: 3355-27-9
• Peso molecular: 705.99
• MDL number: MFCD00063522
• UNSPSC Code: 51191904
• NACRES: NA.25

Propiedades

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850350C-25mg); pkg of 2 × 4 mL (850350C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850350C
• concentration: 10 mg/mL (850350C-25mg); 25 mg/mL (850350C-200mg)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [P](=O)(OCC[N+](C)(C)C)(OCC(OC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)O
• InChI: 1S/C38H76NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39(3,4)5)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/p+1
• InChI key: LJARBVLDSOWRJT-UHFFFAOYSA-O

Descripción

General description

Phosphatidylcholine (PC) carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It is an important component of mammalian membranes.[1]

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

15:0 PC (1,2-dipentadecanoyl-sn-glycero-3-phosphocholine) may be used:

• as a component in fluidizing lipid bilayers to study the role of membrane fluidity in mediating membrane sensitivity to small hydrophobic peptides or haptoglobin-related protein (SHP-1)[2]
• to prepare giant unilamellar lipid vesicles (GUVs)[3]
• to construct supported phospholipid bilayers to study the gel-fluid phase transition behavior using in situ, temperature-dependent atomic force microscopy[4]

Biochem/physiol Actions

Phosphatidylcholine (PC) is capable of preventing the penetrance of bacteria by acting as a surfactant.[5] This phospholipid is capable of forming a strong bilayer.[1]

Packaging

5 mL Clear Glass Sealed Ampule (850350C-200mg)

5 mL Clear Glass Sealed Ampule (850350C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• wgk_germany: WGK 3