850346C

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

• Sinónimos: 1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))
• Fórmula empírica (notación de Hill): C₃₆H₆₈NO₈P
• Número de CAS: 56750-90-4
• Peso molecular: 673.90
• Número MDL: MFCD07784458
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: liquid
• envase: pkg of 1 × 2.5 mL (850346C-25mg); pkg of 2 × 4 mL (850346C-200mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 850346C
• concentración: 10 mg/mL (850346C-25mg); 25 mg/mL (850346C-200mg)
• tipo de lípido: cardiolipins; phospholipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.[1]

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[2] It is also an important component of the mucosal layer of the colon.[3]

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

14:1 (Δ9-Cis) PC has been used in the liposome preparation.[4] It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.[5]

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells.[1] PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia.[6] Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.[7]

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[3] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[6]

Envase

5 mL Clear Glass Sealed Ampule (850346C-200mg)

5 mL Clear Glass Sealed Ampule (850346C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372
• Consejos de prudencia: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Órganos de actuación: Liver,Kidney, Respiratory system
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash