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Merck

840503C

Avanti

18:0-18:1 PG

1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

Sinónimos:

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); SOPG; PG(18:0/18:1(9Z)); 110652

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25 MG
MXP 3,722.00
200 MG
MXP 12,516.00

MXP 3,722.00


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25 MG
MXP 3,722.00
200 MG
MXP 12,516.00

About This Item

Fórmula empírica (notación de Hill):
C42H80O10PNa
Número de CAS:
Peso molecular:
799.04
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

MXP 3,722.00


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Ensayo

>99% (TLC)

Formulario

liquid

envase

pkg of 1 × 2.5 mL (840503C-25mg)
pkg of 2 × 4 mL (840503C-200mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand 840503C

concentración

10 mg/mL (840503C-25mg)
25 mg/mL (840503C-200mg)

tipo de lípido

cardiolipins
phospholipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC(O)CO

InChI

1S/C42H81O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,39-40,43-44H,3-17,19,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b20-18-;/t39?,40-;/m1./s1

Clave InChI

AZUBILBUHSANJX-VDVGXYCESA-M

Descripción general

18:0-18:1 PG (SOPG/1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) is a hydrogenated phospholipid.[1] It has two additional methylene groups in its saturated sn-1 chain. The thylakoid membranes of higher plants and cyanobacteria has phosphatidylglycerol (PG).[2]

Aplicación

18:0-18:1 PG (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used:
  • as a component in biocompatible phospholipid bilayer to coat the gold nanoparticles (GNPs) surface[3]
  • in liposomes preparation[4][1]
  • in the formation of lipid monolayer[1]

Acciones bioquímicas o fisiológicas

Phosphatidylglycerol (PG) helps to maintain the stability of photosystem I and II protein complexes. It is involved in bacterial defense mechanisms.[2]

Envase

5 mL Clear Glass Sealed Ampule (840503C-200mg)
5 mL Clear Glass Sealed Ampule (840503C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Órganos de actuación

Liver,Kidney, Respiratory system

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash


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Jianjun Pan et al.
Biochimica et biophysica acta, 1818(9), 2135-2148 (2012-05-16)
We have determined the molecular structures of commonly used phosphatidylglycerols (PGs) in the commonly accepted biologically relevant fluid phase. This was done by simultaneously analyzing small angle neutron and X-ray scattering data, with the constraint of measured lipid volumes. We
J P Michel et al.
Langmuir : the ACS journal of surfaces and colloids, 33(41), 11028-11039 (2017-09-19)
The outer membrane (OM) of Gram-negative bacteria is a complex and asymmetric bilayer that antimicrobial peptides must disrupt in order to provoke the cell lysis. The inner and external leaflets of the OM are mainly composed of phospholipids (PL), and
J P Michel et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2967-2979 (2015-09-08)
Bacterial resistance to antibiotics has become today a major public health issue. In the development of new anti-infectious therapies, antimicrobial peptides appear as promising candidates. However, their mechanisms of action against bacterial membranes are still poorly understood. We describe for
Meijing Wang et al.
Biochimica et biophysica acta, 1831(6), 1089-1097 (2013-02-06)
Gold nanoparticles (GNPs) have been applied as diagnostic and therapeutic agents because they can be targeted, localized, and be heated to cause cell death. However, their use has been limited by their relatively low biocompatibility. In this work, we coated
Joury S van 't Klooster et al.
eLife, 9 (2020-04-18)
Yeast tolerates a low pH and high solvent concentrations. The permeability of the plasma membrane (PM) for small molecules is low and lateral diffusion of proteins is slow. These findings suggest a high degree of lipid order, which raises the

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