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810175P

Avanti

18:1-06:0 NBD PA

Avanti Research™ - A Croda Brand

Sinónimos:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate (ammonium salt)

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10 MG
MXP 14,152.00

MXP 14,152.00

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10 MG
MXP 14,152.00

About This Item

Fórmula empírica (notación de Hill):
C33H56N5O11P
Número de CAS:
474942-97-7
Peso molecular:
729.80
Número MDL:
MFCD00870345
Código UNSPSC:
12352211
NACRES:
NA.25

MXP 14,152.00

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Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 5 × 2 mg (810175P-10mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Phosphatidic acid (PA) is an amphipathic lipid containing a polar head group and two long hydrophobic acyl chains. PA is an anionic and a membrane structural lipid. It acts as a parent compound for more complex membrane phospholipids.[1]

Aplicación

18:1-06:0 NBD PA may be used for study the effects of NBD-PA induced vesiculation on epidermal growth factor receptor (EGFR) endocytosis in mammalian cells[2] and the co-localization of fluorescently-labeled poly(A)-specific ribonuclease (PARN) with the NBD-tagged PA that outlines the close proximity phospholipase D (PLD2) and PARN.[3]

Acciones bioquímicas o fisiológicas

Phosphatidic acid (PA) is a bioactive lipid and a secondary messenger.[4] PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.[1]

Envase

5 mL Amber Glass Screw Cap Vial (810175P-10mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

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Certificados de análisis (COA)

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Bioactive Lipids
An Introduction to Biological Membranes, , number=(, pages=), 453-478 (2016)
Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Taylor E Miller et al.
Biology open, 6(2), 176-186 (2016-12-25)
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN). The physiological roles and regulation for PARN is
Karen M Henkels et al.
Oncotarget, 7(30), 47002-47017 (2016-06-04)
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not
A Chauhan et al.
Neurochemical research, 25(3), 423-429 (2000-04-13)
Fibrillar amyloid beta-protein (Abeta) is the major protein of amyloid plaques in the brains of patients with Alzheimer's disease (AD). The mechanism by which normally produced soluble Abeta gets fibrillized in AD is not clear. We studied the effect of
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