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790326C

Avanti

Fluorescent Transfection Reagent

Avanti Research™ - A Croda Brand 790326C

Sinónimos:

Fluorescent Transfection Reagent, Fluorescent Transfection Reagent, contains DOTAP:DOPE (1:1, w/w) + 0.1 wt.% NBD-DOPE

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About This Item

Código UNSPSC:
12352202
NACRES:
NA.25

Formulario

liquid

envase

pkg of 1 × 1 mL (790326C-10mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 790326C

concentración

10 mg/mL (790326C-10mg)

aplicaciones

advanced drug delivery

tipo de lípido

cationic lipids
transfection

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

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Descripción general

Fluorescent Transfection Reagent has the cationic lipid 1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride (DOTAP) and the neutral lipid DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine in the ratio 1:1 w/w along with 0.1 wt% N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)dioleoyl (NBD) DOPE. NBD-DOPE is a fluorescence label. NBD is attached to headgroup of DOPE.

Aplicación

Fluorescent Transfection Reagent has been used to visualize the localization of liposome oligodeoxynucleotides (ODN) complex in lung alveolar cells.

Acciones bioquímicas o fisiológicas

Fluorescent Transfection Reagent is useful in understanding fibroplex membrane structure and interaction of fibroin particles with cationic lipids. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)dioleoyl (NBD) is used in model membranes studies and is useful in visualizing membrane domains, at 460/535 nm (excitation/emission) wavelengths. The DOTAP:DOPE with 0.1% NBD-DOPE liposome (LipNBD) reconstituted with transferrin called the transferrin liposome-nitrobenzoxadiazole (Tf-LipNBD) is useful as a probe. It provides improved image contrast in in vitro magnetic resonance imaging (MRI) of tumor cells.

Envase

5 mL Clear Glass Sealed Ampule (790326C-10mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash

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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Growth hormone-dependent changes in the rat lung proteome during alveorization
Beyea JA, et al.
Molecular and Cellular Biochemistry, 321(1-2), 197-197 (2009)
Dual probe with fluorescent and magnetic properties for imaging solid tumor xenografts
Shan L, et al.
Molecular Imaging, 6(2), 7290-2007 (2007)
The influence of NBD fluorescent probe on model membranes containing POPC and DPPC
Weng CJ, et al.
Molecular Membrane Biology, 33(1-2), 23-28 (2016)
Efficiency data of intracellular recombinant protein delivery using cationic lipid coated silk fibroin particle
Kim WJ, et al.
Data in Brief, 13, 683-691 (2017)
Woo-Jin Kim et al.
Biomaterials, 122, 154-162 (2017-01-26)
Directly delivering therapeutic proteins into cells has promise as an intervention without side effects for protein deficiencies caused by genetic defects. However, as negatively charged macromolecules, proteins require carriers for achieving cellular uptake and maintaining their activity in the cytoplasm.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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