Product D28000 (Diazald®) is the suggested alternative for MNNG (1-methyl-3-nitroso-1-nitroguanidine), which has been used for mutagenesis experiments. Unfortunately, Sigma-Aldrich has not tested the affect of Diazald® as a mutagenic agent. It is structurally distinct from MNNG. Products N4766 and N1517 (N-nitroso-N-methylurea), which are recommended for work in mutagenesis, might be more suitable alternatives than product D28000.
D28000
Diazald®
99%
Sinónimos:
N-Methyl-N-(p-tolylsulfonyl)nitrosamide, N-Methyl-N-nitroso-p-toluenesulfonamide, N-Nitroso-N-methyl-p-toluenesulfonamide, N-Nitroso-p-toluenesulfomethylamide, p-Tolylsulfomethylnitrosamide, Diazomethane precursor
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About This Item
Fórmula lineal:
CH3C6H4SO2N(CH3)NO
Número de CAS:
Peso molecular:
214.24
Beilstein/REAXYS Number:
2214345
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
99%
form
solid
mp
61-62 °C (lit.)
SMILES string
CN(N=O)S(=O)(=O)c1ccc(C)cc1
InChI
1S/C8H10N2O3S/c1-7-3-5-8(6-4-7)14(12,13)10(2)9-11/h3-6H,1-2H3
InChI key
FFKZOUIEAHOBHW-UHFFFAOYSA-N
Categorías relacionadas
Application
Storage and Stability
Warning: these products are subject to the Explosives Act and must be transported refrigerated - additional costs for transport will apply.
Legal Information
Diazald is a registered trademark of Merck KGaA, Darmstadt, Germany
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Referencia del producto
Descripción
Precios
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Self-react. C - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
4.1A - Other explosive hazardous materials
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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J. Chem. Soc. Perkin Trans. II, 1233-1233 (1993)
Organometallics, 12, 1029-1029 (1993)
J. Chem. Soc. Perkin Trans. II, 29-29 (1993)
Journal of Chromatographic Science, 29, 8-8 (1991)
Lalit K Golani et al.
Journal of medicinal chemistry, 59(17), 7856-7876 (2016-07-28)
Targeted antifolates with heteroatom replacements of the carbon vicinal to the phenyl ring in 1 by N (4), O (8), or S (9), or with N-substituted formyl (5), acetyl (6), or trifluoroacetyl (7) moieties, were synthesized and tested for selective
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Can Product D28000, Diazald®, be used in mutagenesis studies?
1 answer-
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Is Diazald, Product No. D28000 product light-, moisture-, or heat-sensitive?
1 answer-
Per the MSDS, this product is light- and heat-sensitive. It may decompose and ignite when stored at a temperature above 40oC.
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What solvents can be used to dissolve Product D28000, Diazald®?
1 answer-
According to the 13th edition of the chemicals encyclopedia published by the Royal Society of Chemistry, it is soluble in ether, petroleum ether, benzene, chloroform, carbon tetrachloride. It is also soluble in ethanol.
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