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A10809

Sigma-Aldrich

4′-Hydroxy-3′-methoxyacetophenone

98%

Sinónimos:

Acetovanillone, Apocynin

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25 G
MXP 1,038.00
100 G
MXP 2,718.00

MXP 1,038.00

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25 G
MXP 1,038.00
100 G
MXP 2,718.00

About This Item

Fórmula lineal:
HOC6H3(OCH3)COCH3
Número de CAS:
498-02-2
Peso molecular:
166.17
Beilstein:
637373
Número CE:
207-854-5
Número MDL:
MFCD00008747
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
24890503
NACRES:
NA.22

MXP 1,038.00

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Nivel de calidad

100

Ensayo

98%

Formulario

powder

bp

263-265 °C/17 mmHg (lit.)

mp

112-115 °C (lit.)

cadena SMILES

COc1cc(ccc1O)C(C)=O

InChI

1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3

Clave InChI

DFYRUELUNQRZTB-UHFFFAOYSA-N

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Categorías relacionadas

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
SDBB1075
STBL0772
STBK6806
STBK5573
STBK1089

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Elham Khanicheh et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2187-2192 (2013-08-03)
Antioxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an nicotinamide adenine dinucleotide phosphate oxidase inhibitor with anti-inflammatory properties. We used contrast-enhanced ultrasound molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative
Jingfei Zhang et al.
Neuron, 82(1), 195-207 (2014-03-19)
Complement receptor 3 (CR3) activation in microglia is involved in neuroinflammation-related brain disorders and pruning of neuronal synapses. Hypoxia, often observed together with neuroinflammation in brain trauma, stroke, and neurodegenerative diseases, is thought to exacerbate inflammatory responses and synergistically enhance brain
Julio Madrigal-Matute et al.
Journal of the American Heart Association, 3(4) (2014-08-07)
Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating
Ji Chen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 681-689 (2012-12-26)
Angiotensin-converting enzyme 2 (ACE2) is a lately discovered enzyme catalyzing Angiotensin II into Angiotensin 1-7. Angiotensin II has been reported to impair endothelial progenitor cell (EPC) function and is detrimental to stroke. Here, we studied the role of ACE2 in
Marilena Colaianna et al.
Antioxidants & redox signaling, 18(12), 1385-1399 (2013-01-17)
Psychosocial stress alters the hypothalamic-pituitary-adrenal axis (HPA-axis). Increasing evidence shows a link between these alterations and oxidant elevation. Oxidative stress is implicated in the stress response and in the pathogenesis of neurologic and psychiatric diseases. NADPH oxidases (NOXs) are a
Ver todos los artículos relacionados

Questions

1–5 of 5 Questions  

  1. I'm looking for apocynin. Is A10809 the right product?

    1 answer

    1. Yes, apocynin is a common synonym for 4´-hydroxy-3´-methoxyacetophenone.

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  2. Can I use Product A10809, Apocynin, in cell culture?

    1 answer

    1. We do not specifically test our A10809 product for use in cell culture. However, several papers cite use of this compound in cell culture, in the micromolar range.

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  3. Can I dissolve Product A10809, Apocynin, in water?

    1 answer

    1. According to the chemicals encyclopedia published by the Royal Society of Chemistry, this product is slightly soluble in cold water and freely soluble in hot water. One publication cites preparation of stock solutions of this compound in cell culture medium at 2.5 mg/mL. See Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

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  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. How can I store stock solutions of Product A10809, Apocynin?

    1 answer

    1. While we ourselves have not tested solution stability, one publication cites storage at -20°C of stock solutions of this compound in cell culture medium at 2.5 mg/mL (Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

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