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Sigma-Aldrich

Peptide - GFOGER bioink

suitable for 3D bioprinting applications

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About This Item

Código UNSPSC:
12352201

Formulario

solid

composición

Product components:
Bioink lyophilized powder (100mg)
Preparation solution C (20mL)

temp. de almacenamiento

−20°C

Aplicación

Peptide - GFOGER bioink is optimized for bioprinting applications and can be printed with great fidelity to create a self-supporting 3D scaffold. This bioink has been designed to work easily and accurately with both extrusion-based and ink-jet printers to produce high-quality and reliable prints. Peptide - GFOGER bioink is based on self-assembling peptide hydrogel technology. The resulting hydrogel is a nanofibrous network with a similar nanoscale matrix structure to that of the native extracellular matrix (ECM) in human tissue. This bioink prints without the need for temperature or pH adjustment, UV curing, or addition of reactive cross-linking reagents, all of which can be detrimental to the health of cells. The gelation is simply triggered by the addition of cell culture media.

Peptide - GFOGER bioink is functionalized with the collagen-mimetic peptide GFOGER, to encourage cell adhesion, proliferation and cellular function.

The product is provided as a lyophilized peptide bioink powder and a preparation solution, which allows formulation of gels with different stiffness and rigidity that can emulate specific physical properties of a wide range of different tissue types.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3


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Printable Self-Assembled Peptide Bio-Inks: Promising Future Applications in Nanomedicine.
Das A K, et al
Archives of Nanomedicine: Open Access Journal, 1(3), 56-58 (2018)
Yihua Loo et al.
Nano letters, 15(10), 6919-6925 (2015-07-28)
Printable scaffolds with adequate mechanical strength and stiffness are sought after to ensure viability of printed cells and tissues. We report the first peptide bioinks-lysine-containing hexapeptides that self-assemble into stable, nanofibrous three-dimensional hydrogels with unprecedented stiffness of up to 40

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