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764604

Sigma-Aldrich

Polyethylenimine, linear

average Mn 2100, PDI <1.3

Sinónimos:

PEI

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1 G
MXP 3,780.00

MXP 3,780.00

Disponible para envío el21 de abril de 2025Detalles

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1 G
MXP 3,780.00

About This Item

Fórmula lineal:
(CH2CH2NH)n
Número de CAS:
9002-98-6
Número MDL:
MFCD00039669
Código UNSPSC:
12162002
NACRES:
NA.23

MXP 3,780.00

Disponible para envío el21 de abril de 2025Detalles

Solicitar un pedido a granel

Formulario

liquid

Nivel de calidad

100

mol peso

average Mn 2100

mp

59-64 °C

temperatura de transición

Tm 59-64 °C

PDI

<1.3

temp. de almacenamiento

2-8°C

cadena SMILES

N1CC1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

Clave InChI

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Descripción general

Polyethylenimine(PEI) is a synthetic cationic polymerwith high charge density and chain flexibility. It is the most widelyinvestigated cationic polymer for non-viral delivery of nucleic acids. LinearPEI can be an effective carrier for a wide range of gene medicine including DNAplasmids, small interfering RNAs, and mRNAs. It protects the DNA from theacidic environment and ensures the release of DNA to the cytoplasm.

Aplicación

  • Water-soluble linear poly (ethylenimine) as a superior bifunctional binder for lithium–sulfur batteries: Demonstrates the utility of water-soluble linear polyethylenimine as an effective bifunctional binder that enhances the cycle stability and efficiency of lithium-sulfur batteries, pivotal for advancing battery technology (Liao et al., 2018).

Palabra de señalización

Danger

Frases de peligro

H302,H317,H318,H411

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
MKCV2167
MKCT1323
MKCT1326
MKCT1325
MKCM1906

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Lei Feng et al.
Engineering in life sciences, 20(8), 320-330 (2020-08-11)
As the main immunogen that could stimulate neutralized antibody in pigs, recombinant E2 protein of CSFV was expressed in CHO-dhfr-cells driven by endogenous Txnip promoter from Chinese hamster. Different fragments of Txnip promoter were amplified by PCR from isolated genomic
Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with

Artículos

Delivery of Nucleic Acids Using Polymers

Delivery of Nucleic Acids Using Polymers

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Progress on Nonviral Delivery for CRISPR/Cas9

CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.

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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Hi, I was wondering if this polymer comes as shown or if they are terminated with primary amine groups?

    1 answer

    1. According to the supplier, the structure is exactly as depicted in the image on this product page.

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