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712191

Sigma-Aldrich

COMU®

greener alternative

≥96.5% (TLC), for peptide synthesis

Sinónimos:

(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate

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About This Item

Fórmula empírica (notación de Hill):
C12H19F6N4O4P
Número de CAS:
1075198-30-9
Peso molecular:
428.27
Número MDL:
MFCD11975052
Código UNSPSC:
12352107
ID de la sustancia en PubChem:
329763117
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nombre del producto

COMU®, 97%

Nivel de calidad

100

Ensayo

≥96.5% (TLC)
96.5-103.5% (T)
97%

Formulario

crystals

idoneidad de la reacción

reaction type: Coupling Reactions

características de los productos alternativos más sostenibles

Less Hazardous Chemical Syntheses
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

aplicaciones

peptide synthesis

grupo funcional

amine
ester
ether
nitrile

categoría alternativa más sostenible

, Aligned

temp. de almacenamiento

2-8°C

cadena SMILES

F[P-](F)(F)(F)(F)F.CCOC(=O)C(=NO\C(N1CCOCC1)=[N+](/C)C)C#N

InChI

1S/C12H19N4O4.F6P/c1-4-19-11(17)10(9-13)14-20-12(15(2)3)16-5-7-18-8-6-16;1-7(2,3,4,5)6/h4-8H2,1-3H3;/q+1;-1/b14-10-;

Clave InChI

GPDHNZNLPKYHCN-DZOOLQPHSA-N

Categorías relacionadas

Descripción general

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention". Click here for more information.

Aplicación

COMU – Safer and More Efficient Peptide Coupling Reagent

Advantages
  • Equal or even superior performance to HATU
  • Non-explosive (does not contain benzotriazole moiety)
  • Suitable for solution phase & solid phase peptide synthesis
  • Utmost retention of configuration – low to non-existent racemization
  • High solubility and stability in typical solvents
  • Visual or colorimetric reaction monitoring possible
  • Easy removal of water-soluble by-products
Morpholine-Based Immonium and Halogenoamidinium Salts as Coupling Reagents in Peptide Synthesis

Información legal

COMU is a registered trademark of Luxembourg Bio Technologies Ltd.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCN1327
BCCM7141
BCCJ9683
BCCL1207
BCCH9981

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Protocolos

Amide Coupling in a Box

Amide Coupling in a Box

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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