663190

Ethyl 5-methylindole-2-carboxylate

97%

• Sinónimos: 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• Fórmula empírica (notación de Hill): C₁₂H₁₃NO₂
• Número de CAS: 16382-15-3
• Peso molecular: 203.24
• Número MDL: MFCD00022703
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24884618
• NACRES: NA.22

Propiedades

• Ensayo: 97%
• Formulario: solid
• mp: 160-164 °C
• grupo funcional: ester
• cadena SMILES: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• Clave InChI: KMVFKXFOPNKHEM-UHFFFAOYSA-N

Descripción

Descripción general

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.[1]

Aplicación

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)