453455

(R)-(+)-Glycidyl trityl ether

98%, optical purity ee: 98% (GLC)

• Fórmula empírica (notación de Hill): C₂₂H₂₀O₂
• Número de CAS: 65291-30-7
• Peso molecular: 316.39
• MDL number: MFCD00273368
• UNSPSC Code: 12352005
• PubChem Substance ID: 24868810
• NACRES: NA.22

Propiedades

• assay: 98%
• form: solid
• optical activity: [α]20/D +10.5°, c = 1 in chloroform
• optical purity: ee: 98% (GLC)
• mp: 99-102 °C (lit.)
• SMILES string: C1O[C@H]1COC(c2ccccc2)(c3ccccc3)c4ccccc4
• InChI: 1S/C22H20O2/c1-4-10-18(11-5-1)22(24-17-21-16-23-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17H2/t21-/m1/s1
• InChI key: XFSXUCMYFWZRAF-OAQYLSRUSA-N

Descripción

Application

(R)-(+)-Glycidyl trityl ether may be used in the preparation of (R)-trityl(thiiranylmethyl)ether by reacting with thiourea. It may also be used as a starting material in the multi-step synthesis of (+)-actisonitrile.

Nucleotides with activity against herpes simplex virus 1 and 2, lipid ammonium salts, and thio analogs of phospholipids have been prepared recently through ring-opening of this epoxide with cytosine derivatives, amines, and thiols, respectively.

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)