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426008

Sigma-Aldrich

Carbofuran

98%

Sinónimos:

2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate

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About This Item

Fórmula empírica (notación de Hill):
C12H15NO3
Número de CAS:
1563-66-2
Peso molecular:
221.25
Beilstein/REAXYS Number:
1428746
EC Number:
216-353-0
MDL number:
MFCD00041819
UNSPSC Code:
12352100
PubChem Substance ID:
24866678
NACRES:
NA.22
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Quality Level

100

assay

98%

form

crystals

mp

150-153 °C (lit.)

functional group

amine

SMILES string

CNC(=O)Oc1cccc2CC(C)(C)Oc12

InChI

1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

InChI key

DUEPRVBVGDRKAG-UHFFFAOYSA-N

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General description

Carbofuran is an anticholinesterase carbamate, which is commonly used as a pesticide. Its literature data on toxicity have been reviewed.[1] The effect from exposure to carbofuran has been investigated on acetylcholinesterase (AChE) activity in the brain and muscle of common carp (Cyprinus carpio).[2] Degradation studies using ozone, UV radiation and advanced oxidation processes (AOPs)[3] and by photocatalytic degradation have been investigated.[4] Ultra high performance liquid chromatography (UHPLC) method to determine the carbofuran in water samples have been developed with satisfactory results.[5]

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCW0953
MKCT1015
MKCQ8959
MKCS2626
MKCQ0244

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Degradation of carbofuran by using ozone, UV radiation and advanced oxidation processes.
Benitez FJ, et al.
Journal of Hazardous Materials, 89(1), 51-65 (2002)
Photocatalytic degradation of carbofuran using semiconductor oxides.
Mahalakshmi M, et al.
Journal of Hazardous Materials, 143(1), 240-245 (2007)
Ahmed S A Harabawy et al.
Ecotoxicology and environmental safety, 103, 61-67 (2014-01-28)
The present work aimed to evaluate the toxic effects of two sublethal concentrations of carbofuran pesticide (0.16 and 0.49mg/L, for 35 days) on hematological and blood biochemical parameters of catfish, Clarias gariepinus, and to evaluate the genotoxic potential of carbofuran
R C Gupta
Journal of toxicology and environmental health, 43(4), 383-418 (1994-12-01)
Carbofuran, an anticholinesterase carbamate, is commonly used as an insecticide, nematicide, and acaricide in agricultural practice throughout the world. Due to its widespread use in agriculture, contamination of food, water, and air has become imminent, and consequently adverse health effects
Ratnesh Kumar Sharma et al.
Disease markers, 32(3), 153-163 (2012-03-02)
Various efforts have been made in past in order to predict the underlying mechanism of pesticide-induced toxicity using in vitro and animal models, however, these predictions may or may not be directly correlated with humans. The present study was designed
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