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Merck

410896

Sigma-Aldrich

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone

98%

Sinónimos:

1-[4-(2-Hydroxyethoxy)phenyl]-2-hydroxy-2-methyl-1-propan-1-one, 2-Hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone, 2-Hydroxy-2-methyl-1-[4-(2-hydroxyethoxy)phenyl]propan-1-one, 4-(2-Hydroxyethoxy)phenyl 2-hydroxy-2-propyl ketone

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About This Item

Fórmula lineal:
HOCH2CH2OC6H4COC(CH3)2OH
Número de CAS:
Peso molecular:
224.25
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Quality Level

assay

98%

mp

88-90 °C (lit.)

SMILES string

CC(C)(O)C(=O)c1ccc(OCCO)cc1

InChI

1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3

InChI key

GJKGAPPUXSSCFI-UHFFFAOYSA-N

Application

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone can be used as a photo-initiator to synthesize:
  • Polyacrylamide-grafted chitosan nanoparticles by copolymerization of acrylamide and chitosan nanoparticles.
  • Hydrophobic polyurethane sponge through thiol–ene Click reaction.

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

not determined

flash_point_c

not determined

ppe

Eyeshields, Gloves, type N95 (US)


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Rami El Assal et al.
Scientific reports, 6, 39144-39144 (2016-12-23)
Cancer cells have been increasingly grown in pharmaceutical research to understand tumorigenesis and develop new therapeutic drugs. Currently, cells are typically grown using two-dimensional (2-D) cell culture approaches, where the native tumor microenvironment is difficult to recapitulate. Thus, one of
Deepak Kumar et al.
Cell transplantation, 25(12), 2213-2220 (2016-07-28)
Nucleus pulposus (NP) tissue damage can induce detrimental mechanical strain on the biomechanical performance of intervertebral discs (IVDs), causing subsequent disc degeneration. A novel, photocurable, injectable, synthetic polymer hydrogel (pHEMA-co-APMA grafted with PAA) has already demonstrated success in encapsulating and
Jiangya Ma et al.
Carbohydrate polymers, 151, 565-575 (2016-07-31)
In the present work, a new flocculant, polyacrylamide-grafted chitosan nanoparticles (NCS-g-PAM), was synthesized by the copolymerization of acrylamide (AM) and chitosan nanoparticle (NCS) under ultraviolet irradiation using 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone as photo-initiator. The NCS was prepared by the ionic gelation between chitosan
Xin Zhao et al.
Acta biomaterialia, 49, 66-77 (2016-11-09)
Development of natural protein-based fibrous scaffolds with tunable physical properties and biocompatibility is highly desirable to construct three-dimensional (3D), fully cellularized scaffolds for wound healing. Herein, we demonstrated a simple and effective technique to construct electrospun 3D fibrous scaffolds for
Seok Hee Han et al.
Scientific reports, 7(1), 14068-14068 (2017-10-27)
Despite numerous reports on iontronic devices, there has been no whole circuit working in aqueous media including even power source. Herein, we introduce complete ionic circuits powered by reverse electrodialysis (RED) for the first time without employing any electronic components.

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What solvent is this soluble in?

    1 answer
    1. This product is not tested for solubility. However, various sources report that this compound is soluble in organic solvents such as ethanol, methanol, DMSO, and dimethyl formamide at approximately 30 mg/mL.

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