387800

5-Chloro-2,4,6-trifluoropyrimidine

99%

• Fórmula empírica (notación de Hill): C₄ClF₃N₂
• Número de CAS: 697-83-6
• Peso molecular: 168.50
• Beilstein/REAXYS Number: 610168
• EC Number: 211-807-4
• MDL number: MFCD00191933
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864189
• NACRES: NA.22

Propiedades

• assay: 99%
• refractive index: n20/D 1.439 (lit.)
• bp: 116 °C (lit.)
• density: 1.626 g/mL at 25 °C (lit.)
• SMILES string: Fc1nc(F)c(Cl)c(F)n1
• InChI: 1S/C4ClF3N2/c5-1-2(6)9-4(8)10-3(1)7
• InChI key: GOYNRDSJTYLXBU-UHFFFAOYSA-N

Descripción

Application

5-Chloro-2,4,6-trifluoropyrimidine can be used as a starting material to synthesize:

• 4-azido-5-chloro-2,6-difluoro-pyrimidine by azidation reaction with sodium azide.[1]
• 5-chloro triphenoxy pyrimidine by reacting with tetraphenoxysilane in the presence of tetra butyl ammonium fluoride (TBAF).[2]
• 5-chloro-2,6-difluoropyrimidin-4-amine, and 5-chloro-4,6-difluoropyrimidin-2-amine (9:1 ratio) by reacting with ammonia.[3]
• 5-Chloro-N,N -diethyl-2,6-dipyrimidin-4-amine, by treating with diethylamine and DIPEA.[3]

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter