36815

1-(Diethoxymethyl)imidazole

≥97.0%

• Fórmula empírica (notación de Hill): C₈H₁₄N₂O₂
• Número de CAS: 61278-81-7
• Peso molecular: 170.21
• Beilstein/REAXYS Number: 908482
• MDL number: MFCD00956331
• UNSPSC Code: 12352100
• PubChem Substance ID: 57649666
• NACRES: NA.22

Propiedades

• assay: ≥97.0%
• form: liquid
• refractive index: n20/D 1.464
• density: 1.041 g/mL at 20 °C (lit.)
• functional group: ether
• storage temp.: 2-8°C
• SMILES string: CCOC(OCC)n1ccnc1
• InChI: 1S/C8H14N2O2/c1-3-11-8(12-4-2)10-6-5-9-7-10/h5-8H,3-4H2,1-2H3
• InChI key: NNQBAGFIYBBAFL-UHFFFAOYSA-N

Descripción

General description

1-(Diethoxymethyl)imidazole is an orthoamide protected imidazole. The dianion reacts selectively at the 2 position[1][2] 1-(Diethoxymethyl)imidazole is a 1-substituted imidazoles.[3] Isoprene-mediated lithiation of 1-(diethoxymethyl)imidazole, leads to the preparation of the corresponding 2-lithio intermediate, which reacts with different electrophiles to afford 2-functionalised imidazoles.[3]

Application

1-(Diethoxymethyl)imidazole may be used in the preparation of various hydroxy- and amino-functionalized imidazoles, via isoprene-mediated lithiation followed by reaction with an electrophile.[4]

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 233.6 °F
• flash_point_c: 112.0 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter