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Merck

330000

Sigma-Aldrich

Rose bengal

Dye content 95 %, ≥96% (HPLC)

Sinónimos:

4,5,6,7-Tetrachloro-2′,4′,5′,7′-tetraiodofluorescein disodium salt, Acid Red 94, Bengal Rose B sodium salt, Rose Bengal sodium salt

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1 G
MXP 1,605.00
5 G
MXP 5,527.00

MXP 1,605.00


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1 G
MXP 1,605.00
5 G
MXP 5,527.00

About This Item

Fórmula empírica (notación de Hill):
C20H2Cl4I4Na2O5
Número de CAS:
Peso molecular:
1017.64
Beilstein:
3645857
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
NA.47

MXP 1,605.00


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Nivel de calidad

Ensayo

≥96% (HPLC)

Formulario

solid

composición

Dye content, 95%

técnicas

titration: suitable

color

red to brown

ε (coeficiente de extinción)

≥ 3000 at 350-354 nm
≥12000 at 311-315 nm
≥32000 at 262-266 nm
≥32000 at 513-517 nm
≥98000 at 546-550 nm at 0.04 g/L (H2O + 1ml 1% Na2CO3)

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

cadena SMILES

[Na+].[Na+].[O-]C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C2=C3C=C(I)C(=O)C(I)=C3Oc4c(I)c([O-])c(I)cc24

InChI

1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2

Clave InChI

UWBXIFCTIZXXLS-UHFFFAOYSA-L

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Descripción general

Rose Bengal is a red or rose color dye and is anionic in nature. It is a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodo derivative of fluorescein. It is widely used to detect damage to the ocular surface epithelium in ocular surface diseases such as dry eye and herpetic keratitis. Rose Bengal has mild antiviral potency.[1][2]
Rose Bengal is used to stain dead and degenerating cells and mucus.[3]

Aplicación

Rose Bengal has been used to evaluate acrosome integrity.[4][5] It has also been used to initiate photothrombotic occlusion in blood.[6][7]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Questions

1–4 of 4 Questions  
  1. What is the solubility of Rose Bengal, Product 330000?

    1 answer
    1. According to The Sigma-Aldrich Handbook of Stains, Dyes and Indicators, Rose Bengal is soluble in water at 100 mg/mL, ethanol at 30 mg/mL and 2-methoxyethanol at 60 mg/mL. Conn's Biological Stains (10th Edition) states Rose Bengal has a solubility of 36% in water and 8% in ethanol.

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  2. What types of applications can Product 330000, Rose bengal be used for?

    1 answer
    1. According to the literature, Rose bengal has been used in a used in neutrophil adherence test and as a generator of singlet oxygen when exposed to laser energy. See: McKinnon, J. , Expt. Med., 164, 1864, (1986) and Gamble and Vadas, Science, 242, 97, (1988).

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. What is the quantum yield of Rose bengal, Product 330000?

    1 answer
    1. According to the literature, the quantum yield of Rose bengal is 0.11. See: Seybold, P.G., et al., Calorimetric, photometric and lifetime determinations of fluorescence yields of fluorescein dyes, Photochem. Photobiol., 9, 229-242 (1969).

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