282227

Chlorhexidine

≥99.5%

• Sinónimos: 1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
• Fórmula lineal: [-(CH₂)₃NHC(=NH)NHC(=NH)NHC₆H₄Cl]₂
• Número de CAS: 55-56-1
• Peso molecular: 505.45
• Beilstein/REAXYS Number: 2826432
• EC Number: 200-238-7
• MDL number: MFCD00009673
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857031
• NACRES: NA.22

Propiedades

• assay: ≥99.5%
• form: powder
• impurities: <1.0% water
• mp: 134-136 °C (lit.)
• solubility: water: soluble 0.08% at 20 °C
• SMILES string: Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
• InChI: 1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
• InChI key: GHXZTYHSJHQHIJ-UHFFFAOYSA-N

Descripción

General description

Effect of the chlorhexidine:hydroxypropyl-β-cyclodextrin inclusion compound on in vitro slabs of bovine dentine has been investigated.

Chlorhexidine is a cationic surfactant with broad-spectrum antimicrobial activity. It is used as a disinfectant in periodontal therapy and surgical scrubs.

Application

Chlorhexidine, the "gold standard" in oral antiseptics, has been used to optimize novel slow release chlorhexidine coatings based on fatty acids in surgical sutures. Chlorhexidine, antibacterial agent, has been used in preparaing chlorhexidine-functionalized calcium phosphate nanoparticles, useful for oral hygiene and dental treatment.

Información de seguridad

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H318,H410
• pcodes: P273 - P280 - P305 + P351 + P338 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves