Journal of applied toxicology : JAT, 31(7), 663-670 (2011-01-11)
Thallium (Tl) is a toxic heavy metal and its exposure to the human body causes physiological and biochemical changes due to its interference with potassium-dependent biological reactions. A high-resolution (1)H NMR spectroscopy based metabonomic approach has been applied for investigating
Until now the effect of thallium (Tl) on renal function has not been investigated systematically. Therefore, the dose (5, 10, 15, 20 mg Tl2SO4/kg body wt., intraperitoneally) and time-dependence of renal damage was investigated in diuresis experiments on conscious rats.
The effect of Tl2SO4 (Tl, 2 mg/100 g b.wt.) on renal amino acid excretion and plasma amino acid composition was investigated in 10- and 55-day-old rats. Tl decreased glomerular filtration rate only in adult rats. On the other hand, the
Altered testicular enzyme patterns in rats after long-term exposure to thallium sulphate.
C Gregotti et al.
Journal de toxicologie clinique et experimentale, 5(4), 265-271 (1985-07-01)
Neurobehavioral toxicology and teratology, 8(3), 273-277 (1986-05-01)
Flavor aversions induced by intraperitoneal (IP) and oral (PO) administration of thallium sulfate were compared in a repeated trial, two-bottle preference test. Male Long-Evans rats (N = 6/group) were given 30-min access to a 0.1% saccharin solution followed 20-min later
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
