TPH2
tryptophan hydroxylase 2
Sinónimos:
ADHD7, NTPH
Especie:
Human TPH2 (121278), Mouse Tph2 (216343), Rat Tph2 (317675), domestic guinea pig Tph2 (100724594), Horse TPH2 (100009684), sheep TPH2 (101120314), dog TPH2 (481165), domestic cat TPH2 (101082165), Domestic Rabbit TPH2 (100009100), Zebrafish tph2 (407712) ...Más
ID UniProtKB:
ID del gen:
- Human(121278) Summary: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008]
- Mouse(216343) tryptophan hydroxylase 2
- Rat(317675) tryptophan hydroxylase 2
- domestic guinea pig(100724594) tryptophan hydroxylase 2
- Horse(100009684) tryptophan hydroxylase 2
- sheep(101120314) tryptophan hydroxylase 2
- dog(481165) tryptophan hydroxylase 2
- domestic cat(101082165) tryptophan hydroxylase 2
- Domestic Rabbit(100009100) tryptophan hydroxylase 2
- Zebrafish(407712) tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)
- chicken(408026) tryptophan hydroxylase 2
- naked mole-rat(101714361) tryptophan hydroxylase 2
- cow(100336620) tryptophan hydroxylase 2
- cow(618062) tryptophan hydroxylase 2
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Antibodies
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Aplicación
Monoclonal Anti-TPH2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2990, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
Anti-tph2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
zebrafish
Aplicación
immunohistochemistry
western blot
western blot
Monoclonal Anti-Tryptophan Hydroxylase antibody produced in mouse, clone WH-3, ascites fluid,
Reactividad de especies
human, monkey, rabbit, rat
Aplicación
ELISA
immunohistochemistry
microarray
western blot
immunohistochemistry
microarray
western blot
Small Molecule - Inhibitor
Small Molecule - Precursor
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esiRNA
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