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Merck

TNFSF15

tumor necrosis factor (ligand) superfamily, member 15

Sinónimos:
TL1, TL1A, VEGI, VEGI192A
Especie:
ID UniProtKB:
ID del gen:
  • Human(9966) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(326623) tumor necrosis factor (ligand) superfamily, member 15
  • Rat(252878) tumor necrosis factor (ligand) superfamily, member 15
  • domestic cat(101099505) tumor necrosis factor (ligand) superfamily, member 15
  • chicken(417247) tumor necrosis factor (ligand) superfamily, member 15
  • naked mole-rat(101720658) tumor necrosis factor (ligand) superfamily, member 15
  • domestic guinea pig(100725797) tumor necrosis factor (ligand) superfamily, member 15
  • sheep(101102957) tumor necrosis factor (ligand) superfamily, member 15
  • dog(481688) tumor necrosis factor (ligand) superfamily, member 15
  • cow(514239) tumor necrosis factor (ligand) superfamily, member 15

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TNFSF15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-TNFSF15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

Proteins

Referencia del producto
Descripción
Especie
TL-1A human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TNFSF15,
Especie
human
MISSION® esiRNA, targeting mouse Tnfsf15,
Especie
mouse