TEK
TEK tyrosine kinase, endothelial
Sinónimos:
CD202B, TIE-2, TIE2, VMCM, VMCM1
Especie:
Human TEK (7010), Mouse Tek (21687), Rat Tek (89804), chicken TEK (427368), Zebrafish tek (30747), dog TEK (403714), domestic cat TEK (101091977), cow TEK (280939), domestic guinea pig Tek (100713324), naked mole-rat Tek (101710501)
ID UniProtKB:
ID del gen:
- Human(7010) Summary: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008]
- Mouse(21687) endothelial-specific receptor tyrosine kinase
- Rat(89804) TEK tyrosine kinase, endothelial
- chicken(427368) TEK tyrosine kinase, endothelial
- Zebrafish(30747) TEK tyrosine kinase, endothelial
- dog(403714) TEK tyrosine kinase, endothelial
- domestic cat(101091977) TEK tyrosine kinase, endothelial
- cow(280939) TEK tyrosine kinase, endothelial
- domestic guinea pig(100713324) TEK tyrosine kinase, endothelial
- naked mole-rat(101710501) TEK tyrosine kinase, endothelial
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ELISA
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Especie
Antibodies
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Reactividad de especies
Aplicación
Anti-Tie-2 Antibody, clone 1C5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-TIE2, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-TIE2 (pTyr992) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
Small Molecule - Inhibitor
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Especie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Especie
human
Proteins
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Descripción
Especie
TIE2 (771-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human