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Merck

RARG

retinoic acid receptor, gamma

Sinónimos:
NR1B3, RARC
Especie:
ID UniProtKB:
ID del gen:
  • Human(5916) Summary: This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(19411) retinoic acid receptor, gamma
  • Rat(685072) retinoic acid receptor, gamma
  • domestic guinea pig(100733817) retinoic acid receptor, gamma
  • cow(540425) retinoic acid receptor, gamma
  • sheep(101106414) retinoic acid receptor, gamma
  • domestic cat(101083275) retinoic acid receptor, gamma
  • naked mole-rat(101722573) retinoic acid receptor, gamma
  • dog(486508) retinoic acid receptor, gamma

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Small Molecule - Activator

Referencia del producto
Descripción
Especie
9-cis-Retinoic acid, ≥98% (HPLC),
Especie
human
Ácido retinoico, ≥98% (HPLC), powder,
Especie
mouse, human

Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Isotretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Ácido retinoico, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Ácido retinoico, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Isotretinoin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Ácido retinoico, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
CD437, ≥98% (HPLC), solid,
Especie
human
TTNPB, ,
Especie
human
Ácido retinoico, ≥98% (HPLC), powder,
Especie
mouse, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-RARγ1 Antibody, clone 1C22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, horse, human, monkey, mouse, porcine
Aplicación
affinity binding assay
immunocytochemistry

western blot

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
9-cis-Retinoic acid, ≥98% (HPLC),
Especie
human
TTNPB, ,
Especie
human
Ácido retinoico, ≥98% (HPLC), powder,
Especie
mouse, human

Proteins

Referencia del producto
Descripción
Especie
RAR, γ human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Especie
human
RAR γ-ligand binding domain (150-417) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
RARγ, ligand binding domain (150-417), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human
RAR, γ isoform, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human RARG,
Especie
human
MISSION® esiRNA, targeting mouse Rarg,
Especie
mouse