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Merck

GPBAR1

G protein-coupled bile acid receptor 1

Sinónimos:
BG37, GPCR19, GPR131, M-BAR, TGR5
Especie:
ID UniProtKB:
ID del gen:
  • Human(151306) Summary: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(227289) G protein-coupled bile acid receptor 1
  • Rat(338443) G protein-coupled bile acid receptor 1
  • naked mole-rat(101710900) G protein-coupled bile acid receptor 1
  • domestic guinea pig(100723590) G protein-coupled bile acid receptor 1
  • sheep(101109073) G protein-coupled bile acid receptor 1
  • cow(317756) G protein-coupled bile acid receptor 1
  • domestic cat(101089457) G protein-coupled bile acid receptor 1
  • dog(488521) G protein-coupled bile acid receptor 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GPBAR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Gpbar1,
Especie
mouse
MISSION® esiRNA, targeting human GPBAR1,
Especie
human