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Merck

GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2559) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14399) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
  • Rat(29708) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • dog(489145) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic cat(101093992) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • cow(539194) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • sheep(101117503) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • Horse(100070890) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • naked mole-rat(101720123) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic guinea pig(100720891) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • chicken(395931) gamma-aminobutyric acid (GABA) A receptor, alpha 6

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Especie
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Especie
human
Isoguvacine hydrochloride, solid,
Especie
human
Piperidine-4-sulfonic acid, ,
Especie
human
γ-Aminobutyric acid, ≥99%,
Especie
human, rat

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human
trans-Dehydroandrosterone, ≥99%,
Especie
human, rat
Propofol, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flunitrazepam, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Ro 15-4513, solid,
Especie
rat, human
Picrotoxin, powder,
Especie
human
Pregnenolone sulfate sodium salt, ,
Especie
human
SR-95531, ≥98% (HPLC), powder,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GABAA Receptor (α6 subunit), Cytosolic Loop antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
rat
Aplicación
western blot
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
NO-711 hydrochloride, ≥98% (HPLC),
Especie
human
(±)-Vigabatrin, ,
Especie
human
2,6-Diisopropylphenol, 97%,
Especie
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Flumazenil, >99% (HPLC), solid,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRA6,
Especie
human