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Merck

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

Custom & Knockdown Gene Products

Small Molecule - Agonist

Número de producto
Descripción
Especie
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Especie
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Especie
human
Isoguvacine hydrochloride, solid,
Especie
human
Piperidine-4-sulfonic acid, ,
Especie
human
γ-Aminobutyric acid, ≥99%,
Especie
human, rat

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human
trans-Dehydroandrosterone, ≥99%,
Especie
human, rat
Propofol, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Propofol, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Número de producto
Descripción
Especie
Ro 15-4513, solid,
Especie
rat, human
Picrotoxin, powder,
Especie
human
Pregnenolone sulfate sodium salt, ,
Especie
human
SR-95531, ≥98% (HPLC), powder,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
western blot
Anti-GABRA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S415-24,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S415-24,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
western blot
Anti GABRA5 Antibody, clone 23GB5505, Rabbit Monoclonal, clone 23GB5505, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
NO-711 hydrochloride, ≥98% (HPLC),
Especie
human
(±)-Vigabatrin, ,
Especie
human
2,6-Diisopropylphenol, 97%,
Especie
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Ligand

Número de producto
Descripción
Especie
L-655,708, ≥98% (HPLC), powder,
Especie
human
Flumazenil, >99% (HPLC), solid,
Especie
rat, human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRA5,
Especie
human