CASP3
caspase 3, apoptosis-related cysteine peptidase
Sinónimos:
CPP32, CPP32B, SCA-1
Especie:
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), dog CASP3 (403567), chicken CASP3 (395476), naked mole-rat Casp3 (101712867), domestic guinea pig Casp3 (100718309), cow CASP3 (408016), Domestic Rabbit CASP3 (100008840), sheep CASP3 (443031) ...Más
ID UniProtKB:
ID del gen:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
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Activity Assay
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
western blot
Anti-Caspase-3 Antibody, clone 3J16 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-Caspase 3 antibody produced in mouse, clone 84803.111, purified immunoglobulin, lyophilized powder,
Reactividad de especies
human
Aplicación
western blot
Anti-Caspase 3 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
microarray
western blot
western blot
Anti- active + pro Caspase-3 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Caspase 3 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
Especie
human
esiRNA
Referencia del producto
Descripción
Especie