AR
androgen receptor
Sinónimos:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Especie:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...Más
ID UniProtKB:
ID del gen:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Referencia del producto
Descripción
Especie
Small Molecule - Agonist
Referencia del producto
Descripción
Especie
Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
dog, human, mouse, pig, rabbit, rat
Aplicación
immunohistochemistry
Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
dog, human, mouse, pig, rat
Aplicación
immunohistochemistry
Anti-Androgen Receptor antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-AR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-AR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9255, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Referencia del producto
Descripción
Especie
Small Molecule - Inhibitor
Small Molecule - Ligand
Referencia del producto
Descripción
Especie