1076352

Bretylium tosylate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate
• Empirical Formula (Hill Notation): C₁₈H₂₄BrNO₃S
• CAS Number: 61-75-6
• Molecular Weight: 414.36
• MDL number: MFCD00038731
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749129
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: bretylium
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CC[N+](C)(C)Cc2ccccc2Br
• InChI: 1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: KVWNWTZZBKCOPM-UHFFFAOYSA-M
• Gene Information: human ... SLC6A2(6530)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bretylium tosylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Bretylium Tosylate Injection
• Bretylium Tosylate in Dextrose Injection

Biochem/physiol Actions

Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade; class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable