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T4891

Sigma-Aldrich

Glyceryl tridodecanoate

≥99%

Synonym(s):

1,2,3-Tridodecanoylglycerol, 1,2,3-Trilauroylglycerol, Glycerol trilaurate, Glyceryl trilaurate, Tridodecanoin, Trilaurin

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About This Item

Linear Formula:
[CH3(CH2)10COOCH2]2CHOCO(CH2)10CH3
CAS Number:
538-24-9
Molecular Weight:
639.00
Beilstein:
1730452
EC Number:
208-687-0
MDL number:
MFCD00026559
UNSPSC Code:
12352211
PubChem Substance ID:
24900235
NACRES:
NA.25

biological source

plant

Assay

≥99%

form

powder

mp

46.5 °C (lit.)

functional group

ester

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCC)OC(=O)CCCCCCCCCCC

InChI

1S/C39H74O6/c1-4-7-10-13-16-19-22-25-28-31-37(40)43-34-36(45-39(42)33-30-27-24-21-18-15-12-9-6-3)35-44-38(41)32-29-26-23-20-17-14-11-8-5-2/h36H,4-35H2,1-3H3

InChI key

VMPHSYLJUKZBJJ-UHFFFAOYSA-N

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Application


  • Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization.: This article presents the development of lipid-based nanoparticles for drug delivery, utilizing glyceryl tridodecanoate as a component. The optimized nanoparticles show potential for improved delivery and efficacy of paclitaxel, a chemotherapeutic agent (Dong et al., 2009).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David A Pink et al.
The Journal of chemical physics, 132(5), 054502-054502 (2010-02-09)
We investigated theoretically two competing published scenarios for the melting transition of the triglyceride trilaurin (TL): those of (1) Corkery et al. [Langmuir 23, 7241 (2007)], in which the average state of each TL molecule in the liquid phase is
A Svensson et al.
International journal of pharmaceutics, 281(1-2), 107-118 (2004-08-04)
The incorporation of drugs into Gelucires has been reported to increase the dissolution rate of poorly soluble drugs, often leading to improved drug bioavailability. In pharmaceutical applications, it is important to know how the excipient interacts with the drug, and
P Kalo et al.
Lipids, 31(3), 331-336 (1996-03-01)
Positional isomers (1-butyryl-2X-3Y-rac-glycerol and 2-butyryl-1X-3Y-rac-glycerol; X,Y = long-chain acyls) of saturated triacylglycerols (TAG) within 34 and 40 acyl carbons were shown to separate in two chromatographic peaks on immobilized phenyl(65%)methylsilicone column by gas-liquid chromatography, and on reversed-phase ODS-1 column by
A Sreenivas et al.
Archives of biochemistry and biophysics, 311(2), 229-234 (1994-06-01)
The developing seeds of Actinodaphne hookeri were investigated to delineate their ability to synthesize large amounts of trilaurin. Until 88 days after flowering the embryos contained 71% neutral lipids (NL) and 29% phospholipids (PL) and both these components contained C16:0
H Heiati et al.
Journal of microencapsulation, 15(2), 173-184 (1998-04-09)
Solid lipid nanoparticles (SLNs) were prepared using trilaurine (TL) as the SLN core and phospholipid (PL) as coating. Neutral and negatively charged PLs were used to produce neutral and negatively charged SLNs. An ester prodrug of 3'-azido-3'-deoxythymidine (Zidovudine, AZT), AZT
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