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T2330

Sigma-Aldrich

TSSK2, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

DGS-G, FLJ38613, SPOGA2, STK22B

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10 μG
MXP 10,936.00

MXP 10,936.00

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10 μG
MXP 10,936.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

MXP 10,936.00

Check Cart for Availability

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

product line

PRECISIO® Kinase

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

116-156 nmol/min·mg

mol wt

~66 kDa

UniProt accession no.

Q96PF2

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... TSSK2(23617)

Application

Human TSSK2, active, GST tagged, may be used to study testis-specific serine/threonine-protein kinase that plays a pivotal role in spermiogenesis.

Biochem/physiol Actions

TSSK2, a protein that belongs to Testis-specific serine/threonine-protein kinase family facilitates the spermatid development. It also has a crucial role in the formation and function of sperm cells in the mouse. Mutation in TSSK2 Gene leads to Human Spermatogenesis Impairment.[1]

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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S Nayak et al.
Mechanisms of development, 74(1-2), 171-174 (1998-07-04)
Previously we identified two intronless serine-threonine kinase genes (Tsk1 and Tsk2) located 3 kb apart on mouse chromosome 16 (Galili, N., Baldwin, H.S., Lund, J., Reeves, R., Gong, W., Wang, Z., Roe, B.A., Emanuel, B.S., Nayak, S., Mickanin, C., Budraf
Zhonglin Hao et al.
Molecular human reproduction, 10(6), 433-444 (2004-03-27)
Two members of the human testis-specific serine/threonine (Ser/Thr) kinase family, TSSK 1 and TSSK 2, were cloned and sequenced from a human testis adaptor-ligated cDNA library using a PCR strategy. Within the cDNA, open reading frames (ORF) were defined encoding
Hao Zhang et al.
Journal of andrology, 31(4), 388-392 (2009-11-21)
Tssk2, a member of the testis-specific serine/threonine kinase (TSSK) family, is expressed predominantly in the testis and is crucial for the formation and function of sperm cells in the mouse. Targeted deletion of Tssk1 and Tssk2 in male chimeric mice

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