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T0175

Sigma-Aldrich

Troponin T from human heart

≥60% (SDS-PAGE), lyophilized powder

Synonym(s):

Tn-T

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About This Item

CAS Number:
150901-75-0
MDL number:
MFCD00213049
UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human heart

Quality Level

200

form

lyophilized powder

purified by

affinity chromatography

concentration

≥60% (SDS-PAGE)

technique(s)

ELISA: suitable

solubility

10 mM HCl: 500 μg/mL, clear, colorless

UniProt accession no.

P45379

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... TNNT2(7139)

General description

The cardiac troponin T gene (TNNT2) is located on human chromosome 1 and spans around 17kb. It codes for a 288-amino-acid peptide of 36−39kDa.

Application

Troponin T from human heart has been used in competitive enzyme-linked immunosorbent assay (ELISA) for the quantification of troponin T (TnT).

Biochem/physiol Actions

The tropomyosin-binding subunit of troponin. The cardiac troponin T gene (TNNT2) helps to connect the troponin complex to α-tropomyosin, thereby participates in the modulation of contractile function.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

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