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SMB00111

Sigma-Aldrich

12-Methoxycarnosic acid

≥95% (LC/MS-ELSD)

Synonym(s):

Carnosic acid 12-methyl ether

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About This Item

Empirical Formula (Hill Notation):
C21H30O4
CAS Number:
62201-71-2
Molecular Weight:
346.46
MDL number:
MFCD24849312
UNSPSC Code:
12352205
PubChem Substance ID:
329824789
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

COc1c(O)c2c(CC[C@H]3C(C)(C)CCC[C@]23C(O)=O)cc1C(C)C

InChI

1S/C21H30O4/c1-12(2)14-11-13-7-8-15-20(3,4)9-6-10-21(15,19(23)24)16(13)17(22)18(14)25-5/h11-12,15,22H,6-10H2,1-5H3,(H,23,24)/t15-,21+/m0/s1

InChI key

QQNSARJGBPMQDI-YCRPNKLZSA-N

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General description

12-Methoxycarnosic acid is a natural product derived from a plant source. It is a diterpene and can be sourced from Salvia microphylla.

Application

12-Methoxycarnosic acid has been used as a standardin high performance liquid chromatography (HPLC),to identify major constituents in rosemary leaves.

Biochem/physiol Actions

12-Methoxycarnosic acid is known to possess in vitro antileishmanial activity. It also functions as an antioxidant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Constituents of Salvia microphylla
Aydo?mus Z, et al.
Natural product research, 20(8) (2006)
Promotion of hair growth by Rosmarinus officinalis leaf extract
Murata K, et al.
Phytotherapy Research, 27(2) (2013)
Supercritical fluid extracts of rosemary leaves exhibit potent anti-inflammation and anti-tumor effects
Peng CH, et al.
Bioscience, Biotechnology, and Biochemistry, 71(9) (2007)
Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth.(Lamiaceae)
Mokoka TA, et al.
South African Journal of botony, 90(9) (2014)

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