SAB5702849

Anti-LEF1 Antibody, clone 9I9T4, Rabbit Monoclonal

• Synonym(s): LEF-1, TCF10, TCF1ALPHA, TCF7L3
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 9I9T4, monoclonal
• form: liquid
• mol wt: 30-50 kDa
• species reactivity: mouse, mouse
• concentration: 0.28 mg/mL
• technique(s): immunofluorescence: 1:100 - 1:500; immunohistochemistry: 1:500 - 1:900; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: LADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHA
• UniProt accession no.: Q9UJU2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LEF1(51176)

Description

General description

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LEF1 (Q9UJU2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1