SAB5702188

Anti-Rad21 Antibody, clone 9H0H6, Rabbit Monoclonal

• Synonym(s): CDLS4, HR21, HRAD21, MCD1, NXP1, SCC1, hHR21
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 9H0H6, monoclonal
• form: liquid
• mol wt: 130 kDa
• species reactivity: rat, human, rat
• concentration: 1.2 mg/mL
• technique(s): ChIP: 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: EKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII
• UniProt accession no.: O60216
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... RAD21(5885)

Description

General description

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 532-631 of human Rad21 (O60216).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, ChIP

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1