SAB5701956

Anti-Phospho-TMEM173-S366 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• concentration: 0.76 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q86WV6
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer366)
• Gene Information: human ... TMEM173(340061)

Description

General description

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Immunogen

A phospho specific peptide corresponding to residues surrounding S366 of human TMEM173.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable