SAB4300229

Anti-phospho-BCL2L11 (pSer⁶⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-BAM antibody produced in rabbit, Anti-BCL2-like 11 (apoptosis facilitator) antibody produced in rabbit, Anti-BIM antibody produced in rabbit, Anti-BIM-alpha6 antibody produced in rabbit, Anti-BIM-beta6 antibody produced in rabbit
• MDL number: MFCD02095895
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~23 kDa
• species reactivity: mouse, rat, human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• isotype: IgG
• immunogen sequence: (P-A-SP-P-G)
• NCBI accession no.: NP_006529.1
• UniProt accession no.: O43521
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer69)
• Gene Information: human ... BCL2L11(10018)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G), according to the protein BCL2L11.

Features and Benefits

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Target description

Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable