SAB4300154

Anti-phospho-HDAC2 (pSer³⁹⁴) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-RPD3 antibody produced in rabbit, Anti-YAF1 antibody produced in rabbit, Anti-histone deacetylase 2 antibody produced in rabbit
• MDL number: MFCD02686596
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~60 kDa
• species reactivity: rat, mouse, human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (E-D-SP-G-D)
• NCBI accession no.: NP_001518.2
• UniProt accession no.: Q92769
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer394)
• Gene Information: human ... HDAC2(3066)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 394 (E-D-S(p)-G-D), according to the protein HDAC2.

Features and Benefits

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Target description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable