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SAB4300105

Sigma-Aldrich

Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-HDACL1 antibody produced in rabbit, Anti-RPD3 antibody produced in rabbit, Anti-histone deacetylase 8 antibody produced in rabbit

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100 μG
MXP 7,930.00

MXP 7,930.00

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100 μG
MXP 7,930.00

About This Item

MDL number:
MFCD02686596
UNSPSC Code:
12352203
NACRES:
NA.41

MXP 7,930.00

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~42 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200

isotype

IgG

immunogen sequence

(R-A-SP-M-V)

NCBI accession no.

NP_001159890.1

UniProt accession no.

Q9BY41

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer39)

Gene Information

human ... HDAC8(55869)

Immunogen

Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8.

Features and Benefits

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Target description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
871511128

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