SAB4200590

Anti-WHAMM (C-terminal) Produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• form: buffered aqueous solution
• mol wt: ~100 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): immunoblotting: 1-2 μg/mL using whole extracts of HEK-293T cells overexpressing human WHAMM.
• UniProt accession no.: Q8TF30
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... WHAMM(123720)

Description

General description

WASP homologue associated with actin, membranes, and microtubules (WHAMM) is a nucleation promoting factor. It is located in the cis-Golgi and tubulo-vesicular membrane transport intermediates. WHAMM contains an N-terminal region, a coiled-coil region and a WCA region. It is located on the human chromosome at 15q25.2.

Specificity

Anti- WHAMM (C-terminal) recognizes human WHAMM.

Immunogen

peptide corresponding to the C-terminal region of human WHAMM , conjugated to KLH.

Application

Anti-WHAMM (C-terminal) produced in rabbit may be used in immunoblotting.

Biochem/physiol Actions

WASP homologue associated with actin, membranes, and microtubules (WHAMM) takes part in actin-related protein 2 & 3 (Arp2/3)-mediated actin polymerization, mediates Golgi membrane association and microtubule dynamics. It also takes part in the maintenance of Golgi structure and participates in vesicle transport between the endoplasmic reticulum and the Golgi apparatus.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Storage and Stability

For continuous use, store at 2–8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable