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Key Documents

PZ0030

Sigma-Aldrich

Filibuvir

≥98% (HPLC)

Synonym(s):

(R)-6-Cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, PF 00868554, PF-00868554

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5 MG
MXP 2,093.00
25 MG
MXP 8,479.00

MXP 2,093.00

Estimated to ship onApril 08, 2025

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5 MG
MXP 2,093.00
25 MG
MXP 8,479.00

About This Item

Empirical Formula (Hill Notation):
C29H37N5O3
CAS Number:
877130-28-4
Molecular Weight:
503.64
UNSPSC Code:
51111800
NACRES:
NA.77

MXP 2,093.00

Estimated to ship onApril 08, 2025

Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

room temp

InChI

1S/C29H37N5O3/c1-5-22-14-20(15-23(6-2)31-22)11-12-29(21-9-7-8-10-21)17-25(35)24(27(36)37-29)16-26-32-28-30-18(3)13-19(4)34(28)33-26/h13-15,21,35H,5-12,16-17H2,1-4H3/t29-/m1/s1

InChI key

SLVAPEZTBDBAPI-GDLZYMKVSA-N

Biochem/physiol Actions

Filibuvir is an orally available, potent and selective inhibitor of the hepatitis C virus (HCV) nonstructural 5B (NS5B) RNA-dependent RNA polymerase that exhibits potent antiviral activity against subgenomic HCV replicons in cell culture assays. Also, Filibuvir potently inhibits viral replication in infected patients. Filibuvir interacts with the thumb site II of the viral polymerase.
Filibuvir is an orally available, potent and selective inhibitor of the hepatitis C virus (HCV) nonstructural 5B (NS5B) RNA-dependent RNA polymerase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000147777
0000147777
044M4732V

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