The epitope recognized by PLA0136 maps to a region between residue 700 and the C-terminus (residue 759) of human Cullin 4A using the numbering given in entry NP_001008895.1 (GeneID 8451).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Cul4a is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Several Cul4 E3 ligase complexes have been identified as important in cell cycle regulation and the DNA damage checkpoint response.
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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