P5171
Endoproteinase Arg-C from mouse submaxillary gland
Type XX-S, lyophilized powder, 250-800 units/mg protein (Lowry)
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About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
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type
Type XX-S
Quality Level
form
lyophilized powder
specific activity
250-800 units/mg protein (Lowry)
composition
Protein, 3.0-7.0%
analyte chemical class(es)
amino acids
storage temp.
2-8°C
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Unit Definition
One unit will hydrolyze 1.0 μmole of Nα-p-tosyl-L-arginine methyl ester per min at pH 8.0 at 25 °C.
Physical form
Lyophilized powder containing NaCl and sodium acetate
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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Ling Liu et al.
Biochemical and biophysical research communications, 407(2), 283-287 (2011-03-08)
Systemic or local delivery of human tissue kallikrein gene (hTK) has been shown to be an effective strategy to alleviate cerebral ischemia/reperfusion (I/R) injury, and tissue kallikrein (TK) administration can suppress glutamate- or acidosis-mediated neurotoxicity in vitro. In the present
Ibeth Guevara-Lora et al.
Peptides, 32(6), 1193-1200 (2011-05-10)
Bradykinin-related peptides, kinins, ubiquitously occur in the nervous system and together with other pro-inflammatory mediators contribute to pathological states of that tissue such as edema and chronic pain. In the current work we characterized the kinin-forming system of neuronal cells
Régine Chambrey et al.
Current opinion in nephrology and hypertension, 20(5), 523-528 (2011-06-29)
Recent studies have provided compelling evidence that tissue kallikrein exerts kinin-independent effects on several renal transporters including the epithelial Na⁺ channel (ENaC), the epithelial calcium channel TRPV5 (transient receptor potential channel vanilloid subtype 5), and the colonic H⁺,K⁺-ATPase. This review
Yoshika Yasuda et al.
Biological & pharmaceutical bulletin, 34(9), 1518-1521 (2011-09-02)
Oral formulation of tissue kallikrein consists primarily of porcine pancreatic kallikrein (PPK) and is used to improve peripheral circulation, menopausal symptoms, and impaired chorioretinal circulation. Although gastrointestinal absorption of tissue kallikrein after oral administration has been reported in nonclinical and
Yi-Dong Wang et al.
European neurology, 65(4), 208-214 (2011-03-23)
Kallikrein, a serine proteinase, has been reported to have many functions, such as selectively dilating arterioles in the ischemic area and enhancing angiogenesis and neurogenesis. Therefore, it may promote cerebral poststroke reorganization. We observed the effect of human tissue kallikrein
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