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About This Item
Empirical Formula (Hill Notation):
C6H8N2O8
CAS Number:
Molecular Weight:
236.14
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
form
powder
contains
~60% lactose
color
white
solubility
organic solvents: soluble (alcohol, acetone and ether)
SMILES string
[H][C@@]1([C@@]([H])(O[N+]([O-])=O)CO2)[C@@]2([H])[C@]([H])(O[N+]([O-])=O)CO1
InChI
1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2
InChI key
MOYKHGMNXAOIAT-UHFFFAOYSA-N
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Biochem/physiol Actions
Nitric oxide (NO) donor and nitrovasodilator. Induces stimulation of corpus mucin biosynthesis in vivo. Used to study the role of nitric oxide in the control of cell growth.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Desen. Expl. 3
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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C Sciorati et al.
British journal of pharmacology, 122(4), 687-697 (1998-01-10)
1. The role of nitric oxide (NO) in the control of cell growth is controversial since both stimulation and (more often) inhibition have been demonstrated in various cell types. In order to reinvestigate the problem and identify the sites of
Benjamin Medalion et al.
The Journal of thoracic and cardiovascular surgery, 150(3), 607-612 (2015-07-21)
Bilateral internal thoracic artery grafting in elderly patients is controversial. We compared the outcome of bilateral internal thoracic artery grafting with that of single internal thoracic artery and saphenous vein and radial artery conduits in these patients. Patients aged 70 years
S Fujii et al.
The American journal of physiology, 274(5 Pt 1), G857-G862 (1998-06-05)
Recently, in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging have been widely used to investigate free radical distribution and metabolism in tissues, organs, and whole body of small animals. Endogenous nitric oxide (NO) is an attractive target of this
Yongliang Jia et al.
International journal of cardiology, 157(3), 330-340 (2011-01-22)
Danshen dripping pill (DSP) is a popular Chinese medicinal product and often compared with isosorbide dinitrate (ISDN) in treating coronary heart disease angina pectoris. Over 100 randomized controlled trials (RCT) have been published in Chinese language but have not been
Lidong Na et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 301-306 (2012-11-20)
The purpose of this paper is to study the potential of N-succinyl chitosan as a novel permeation enhancer for the intranasal absorption of isosorbide dinitrate (ISDN). A series of N-succinyl chitosan (NSCS) with different degree of succinylation (DS) and molecular
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