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CRG-2 from mouse

Name: CRG-2 from mouse
Brand: SIGMA

BioReagent, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture

Synonym(s):

CXCL10, Cytokine Responsive Gene 2, IP-10

About This Item

UNSPSC Code:

12352209

NACRES:

NA.75

MDL number:

MFCD01866130

This product is discontinued. Contact Technical Servicefor assistance.

Properties

recombinant

expressed in E. coli

product line

BioReagent

assay

≥97% (SDS-PAGE)

form

lyophilized powder

mol wt

predicted mol wt ~8.8 kDa

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P17515

storage temp.

−20°C

Gene Information

mouse ... Cxcl10(15945)

Description

General description

Recombinant Mouse CRG-2 is produced from a DNA sequence encoding the mature mouse CRG-2/IP-10 protein sequence (MIPLARTVRCNCHIHIDDGPVRMRAIGKLEIIPASLSCPRVEIIATMKKNDEQRCLNPESKTI KNLMKAFSQKRSKRAP). The methionyl form of the E. coli-expressed mature CRG-2 contains 78 amino acid residues and has a predicted molecular mass of approximately 8.8 kDa.

Recombinant Mouse CRG-2 (IP-10, CXCL10) is a member of the chemokine ??subfamily that lacks the ELR domain. Mouse CRG-2 cDNA encodes a 98 amino acid residue precursor protein with a 21 amino acid residue signal peptide that is cleaved to form the 77 amino acid residue secreted mature protein. Mature mouse CRG-2 shares approximately 67% amino acid sequence identity with human IP-10.

Physical form

Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4, containing 50 μg bovine serum albumin per 1 μg of cytokine

Analysis Note

The biological activity is measured by its ability to chemoattract human lymphocytes cultured in the presence of IL-2 for 21 days, or mouse BaF/3 cells transfected with hCXCR-3.

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1 of 1

This Item	SRP3216	SRP3240	I3400
SAFC C8490 CRG-2 from mouse	Sigma-Aldrich SRP3216 KC (CXCL1) from mouse	Sigma-Aldrich SRP3240 GRO/KC (CXCL1) from rat	Sigma-Aldrich I3400 Interferon-γ-Inducible Protein-10 human
form lyophilized powder	form lyophilized	form lyophilized	form lyophilized powder
impurities endotoxin, tested	impurities <0.1 EU/μg endotoxin, tested	impurities <0.1 EU/μg endotoxin, tested	impurities endotoxin, tested
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -
assay ≥97% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)	assay ≥97% (SDS-PAGE)
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Gene Information mouse ... Cxcl10(15945)	Gene Information mouse ... CXCL1(14825)	Gene Information rat ... CXCL1(81503)	Gene Information human ... CXCL10(3627)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

SLBD7240V

084K0952

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Global Trade Item Number

SKU	GTIN
C8490-10UG	04061832296920

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