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C0605

Sigma-Aldrich

Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone

≥90% (HPLC)

Synonym(s):

Z-DEVD-FMK

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About This Item

Empirical Formula (Hill Notation):
C30H41N4O12F
CAS Number:
210344-95-9
Molecular Weight:
668.66
MDL number:
MFCD23380217
UNSPSC Code:
12352200
PubChem Substance ID:
329774802

Assay

≥90% (HPLC)

form

powder

color

off-white

solubility

DMSO: ≥20 mg/mL, clear

shipped in

dry ice

storage temp.

−20°C

SMILES string

COC(=O)CC[C@H](NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

InChI

1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1

InChI key

GBJVAVGBSGRRKN-JYEBCORGSA-N

Biochem/physiol Actions

A cell-permeable inhibitor of caspase 3, 6, 7, 8, 10, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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