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B2129

L-Aspartic acid β-benzyl ester

≥98%

Synonym(s):

β-Benzyl L-aspartate, L-Aspartic acid 4-benzyl ester

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25 g
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MXP 6,904.00
MXP 5,178.00

About This Item

Linear Formula:
C6H5CH2OCOCH2CH(NH2)COOH
CAS Number:
Molecular Weight:
223.23
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
218-541-8
MDL number:
Beilstein/REAXYS Number:
1983183

MXP 5,178.00

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Product Name

L-Aspartic acid β-benzyl ester,

assay

≥98%

Quality Level

form

powder

color

white

mp

225 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

N[C@@H](CC(=O)OCc1ccccc1)C(O)=O

InChI

1S/C11H13NO4/c12-9(11(14)15)6-10(13)16-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,14,15)/t9-/m0/s1

InChI key

VGALFAWDSNRXJK-VIFPVBQESA-N

Application

L-Aspartic acid β-benzyl ester is used in the synthesis of peptides with a 1,4-diazepine-2,5-dione ring structure and in development of block copolymers.

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This Item
A1057B900311260
form

powder

form

powder

form

powder

form

powder or crystals

assay

≥98%

assay

≥98%

assay

≥98% (TLC)

assay

≥97.0% (KT)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

color

white

color

white to off-white

color

white to off-white

color

white to faint beige

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mp

225 °C

mp

-

mp

95-99 °C

mp

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Chander Amgoth et al.
Journal of materials chemistry. B, 8(40), 9258-9268 (2020-09-25)
Herein, the synthesis of an amino-acid-based di-block copolymer (di-BCP) in-between an l-glutamic acid-5-benzyl ester and l-aspartic acid-4-benzyl ester [(l-GluA-5-BE)-b-(l-AspA-4-BE)] has been reported. However, the synthesis of di-BCP of [(l-GluA-5-BE)-b-(l-AspA-4-BE)] was carried out through the facile modified ring-opening polymerization (ROP) without
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting.
Opanasopit P, Yokoyama M, et al.
Pharmaceut. Res., 21, 2001-2008 (2004)
Helga Süli-Vargha et al.
Journal of peptide science : an official publication of the European Peptide Society, 13(11), 742-748 (2007-09-14)
The Fmoc-based SPPS of H-Xaa-Asp(OBzl)-Yaa-Gly-NH(2) sequences results in side reactions yielding not only aspartimide peptides and piperidide derivatives, but also 1,4-diazepine-2,5-dione-peptides. Evidence is presented to show that the 1,4-diazepine-2,5-dione derivative is formed from the aspartimide peptide. The rate of this



Global Trade Item Number

SKUGTIN
B2129-25G04061832421346

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