88930
Thionin acetate salt
for microscopy (Bact., Bot., Hist.)
Synonym(s):
3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet
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About This Item
Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
Molecular Weight:
287.34
Colour Index Number:
52000
Beilstein:
4345073
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
grade
for microscopy (Bact., Bot., Hist.)
form
powder
technique(s)
titration: suitable
SMILES string
CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1
InChI
1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1
InChI key
OWXBIRAFHWASMS-UHFFFAOYSA-M
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Application
Thionine (Lauth′s violet), a metachromatic dye, is widely used as a biological stain of materials such as DNA. Thionine is being studied as an electron mediator in the development of microbial fuel cells and electrochemical biosensors.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Liu Deng et al.
Analytical chemistry, 82(10), 4283-4287 (2010-04-21)
In this work we developed a fully integrated biofuel cell on a microchip, which consisted of glucose dehydrogenase supported (carbon nanotubes/thionine/gold nanoparticles)(8) multilayer as the anode, and the (carbon nanotubes/polylysine/laccase)(15) multilayer as the cathode. The as-obtained biofuel cell produced open
Ling Meng et al.
Biosensors & bioelectronics, 24(6), 1751-1756 (2008-10-24)
A glutamate biosensor based on the electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide (NADH), which was generated by the enzymatic reaction, was developed via employing a single-walled carbon nanotubes/thionine (Th-SWNTs) nanocomposite as a mediator and an enzyme immobilization matrix. The
Yunying Xie et al.
Analytica chimica acta, 699(1), 44-48 (2011-06-28)
We reported a graphene-based immunosensor for electrochemical quantification of phosphorylated p53 on serine 15 (phospho-p53(15)), a potential biomarker of gamma-radiation exposure. The principle is based on sandwich immunoassay and the resulting immunocomplex is formed among phospho-p53 capture antibody, phospho-p53(15) antigen
Selvaraj Baskar et al.
Biosensors & bioelectronics, 33(1), 95-99 (2012-01-24)
We report here a novel detection scheme for simultaneous detection of NADH and H(2)O(2) based on a bifunctional poly(thionine)-modified electrode. Electropolymerization of thionine on a "preanodized" screen-printed carbon electrode effectively lowers the oxidation potential of NADH to 0.15 V (vs.
Zhanxia Zhang et al.
Journal of the American Chemical Society, 135(5), 1934-1940 (2013-01-10)
The fluorescent dyes methylene blue, MB(+), and thionine, Th(+), can be trapped in the pores of mesoporous silica, MP-SiO(2), by means of functional nanostructures consisting of the Mg(2+)- or Zn(2+)-dependent DNAzyme sequences. In the presence of Mg(2+) or Zn(2+) ions
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